The historic 8.9 acre site has 130 metres of river frontage and is located between the centre of Greenwich and the O2.
In addition to new homes, the site has detailed planning permission for a cruise terminal, a 250 room hotel, commercial space and the restoration of the historic Grade II listed Enderby House that was built in the 1830s.
Barratt London will start construction of the residential elements, including 154 affordable homes, in the autumn of 2013.